Video: Cell Cycle and Mitosis

 

The following video discusses the cell cycle and mitosis:

Video 1. Cell Cycle and Mitosis (opens YouTube in new window)

 

 

Phases of Mitosis

 

Table 1. Phases of Mitosis
Prophase Prometaphase Metaphase Anaphase Telophase Cytokinesis
prophase prophase metaphase anaphase telophase cytokinesis
  • Chromosome condense and become visible
  • Spindle fibers emerge from the centrosome
  • Nuclear envelope breaks down
  • Nucleolus disappears
  • Chromosomes continue to condense
  • Kinetochores appear at the Centrosome
  • Mitotic spindle microtubules attach to Kinetochores
  • Centrosomes move toward opposite poles

 

 

  • Mitotic spindle is fully developed; centrosomes are at opposite poles of the cell
  • Chromosomes are lined up at the metaphase plate
  • Each sister chromatid is attached to a spindle fiber originating from opposite poles

 

  • Cohesion proteins binding the sister chromatids together break down
  • Sister chromatids (now called chromosomes) are pulled toward opposite poles
  • Non-kinetochore spindle fibers lengthen, elongating the cell
  • Chromosomes arrive at opposite poles and begin to de-condense
  • Nuclear envelope material surrounds each set of chromosomes
  • The mitotic spindle breaks down
  • Animal cells: a cleavage furrow separates the daughter cells
  • Plant cells: a cell plant separates the daughter cells
prophase prometaphase metaphase anaphase telophase cytokinesis